Sobredosis por bloqueadores de calcio en una mujer
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Date
Subject
calcium channel blockers
drug overdose
toxicity
bloqueadores canales de calcio
sobredosis medicamentosa
toxicidad
drug overdose
toxicity
bloqueadores canales de calcio
sobredosis medicamentosa
toxicidad
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Journal ISSN
Volume Title
Publisher
Intituto Tecnológico de Santo Domingo (INTEC)
Los bloqueadores de los canales de calcio son un tipo de medicamento comúnmente utilizado para enfermedades como la hipertensión, la fibrilación auricular, la enfermedad de las arterias coronarias. La sobredosis con este medicamento puede causar efectos adversos fatales, como el colapso cardiovascular; por lo tanto, es importante identificar y tratar a estos pacientes lo antes posible. El tratamiento para la toxicidad del bloqueador de los canales de calcio está respaldado por evidencia de baja calidad en la literatura médica. Presentamos el caso de una paciente de 19 años que se intoxica con el bloqueador de los canales de calcio nifedipina. La paciente llegó a la sala de emergencias 20 horas después de la ingestión de 53 tabletas de nifedipina de 10 mg cada una, presentándose en el departamento de emergencias con hipotensión y síntomas de emesis repetida después de ingerir líquidos y alimentos sólidos. Posteriormente, la paciente sufrió un shock cardiogénico que condujo a la admisión a la UCI cardiovascular, que requirió intubación, noradrenalina y soporte dopaminérgico. Durante su estadía en la UCI Cardiovascular, la paciente presentó neumonía por aspiración; después del 7º día en la unidad, fue transferida a la sala clínica y después del 4º día en esa área se recuperó por completo y fue dada de alta después de ser evaluada por el departamento de psiquiatría. Aquí presentamos un caso de sobredosis de nifedipina tratado con éxito, el cual es un tema que se subestima y del cual no se posee suficiente evidencia en cuanto manejo adecuado de estos pacientes.
Calcium channel blockers are a type of commonly used medication for diseases such as hypertension, atrial fibrillation, coronary artery disease. Overdose with this medication can cause fatal adverse effects such as cardiovascular collapse, therefore it is important to identify and treat as early as possible these patients. Treatment for calcium channel blocker toxicity is supported by low-quality evidence in the medical literature. We present the case of a 19-year-old female patient that got intoxicated with the calcium channel blocker nifedipine. The patient came to the ER 20 hours after ingestion of 53 tablets of nifedipine of 10 mg each, presenting at the Emergency department hypotension and symptoms of repeated emesis after ingesting liquids and solid foods. The patient subsequently went into cardiogenic shock which led to Cardiovascular ICU admission, requiring intubation, noradrenaline, and dopaminergic support. During her stay in the Cardiovascular ICU, the patient presented aspiration pneumonia; after 7th day in the unit, she was transferred to the clinical ward and after day 4th in that area she made full recovery and was discharged after being evaluated by the psychiatry department. Here we present a successfully treated case of nifedipine overdose, which is a subject that is underappreciated and has weak evidence without a consensus on how to appropriately treat these patients.
Calcium channel blockers are a type of commonly used medication for diseases such as hypertension, atrial fibrillation, coronary artery disease. Overdose with this medication can cause fatal adverse effects such as cardiovascular collapse, therefore it is important to identify and treat as early as possible these patients. Treatment for calcium channel blocker toxicity is supported by low-quality evidence in the medical literature. We present the case of a 19-year-old female patient that got intoxicated with the calcium channel blocker nifedipine. The patient came to the ER 20 hours after ingestion of 53 tablets of nifedipine of 10 mg each, presenting at the Emergency department hypotension and symptoms of repeated emesis after ingesting liquids and solid foods. The patient subsequently went into cardiogenic shock which led to Cardiovascular ICU admission, requiring intubation, noradrenaline, and dopaminergic support. During her stay in the Cardiovascular ICU, the patient presented aspiration pneumonia; after 7th day in the unit, she was transferred to the clinical ward and after day 4th in that area she made full recovery and was discharged after being evaluated by the psychiatry department. Here we present a successfully treated case of nifedipine overdose, which is a subject that is underappreciated and has weak evidence without a consensus on how to appropriately treat these patients.
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Type
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/publishedVersion
Source
Science and Health; Vol. 5 No. 1 (2021): Science and Health, january-april; 109-116
Ciencia y Salud; Vol. 5 Núm. 1 (2021): Ciencia y Salud, enero-abril; 109-116
2613-8824
2613-8816
10.22206/cysa.2021.v5i1
Ciencia y Salud; Vol. 5 Núm. 1 (2021): Ciencia y Salud, enero-abril; 109-116
2613-8824
2613-8816
10.22206/cysa.2021.v5i1