Sepsis en pacientes con tumores sólidos en quimioterapia
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Subject
oncological patient
sepsis
solid tumor
chemotherapy
paciente oncológico
sepsis
tumor sólido
quimioterapia
sepsis
solid tumor
chemotherapy
paciente oncológico
sepsis
tumor sólido
quimioterapia
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Journal Title
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Volume Title
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Intituto Tecnológico de Santo Domingo (INTEC)
El cáncer constituye un problema de salud mundial. Múltiples factores relacionados con la enfermedad y los tratamientos provocan predisposición a las infecciones en el paciente oncológico. La sepsis, constituye una importante causa de morbimortalidad. Se realizó un estudio descriptivo de corte transversal, con el objetivo de describir el comportamiento de las infecciones en pacientes con tumores sólidos en quimioterapia, atendidos en el servicio de Oncología Médica del Hospital Clínico Quirúrgico Hermanos Ameijeiras, de enero 2015 a enero 2017. La media de edad fue 53 años (32,3 %) y predominaron los pacientes masculinos (56.5 %). Los tumores de vías digestivas, carcinomas de pulmón y sarcomas de partes blandas representaron el 32.3, 25 y 13.7 %, respectivamente. De los 124 eventos de sepsis reportados, el 39.5 % fueron neutropenia febril, seguido por sepsis urinaria (34.7 %). En pacientes con otras infecciones, predominaron la nuemopatía inflamatoria y la mucositis grado IV. No existió asociación estadística significativa entre el esquema de quimioterapia y la aparición de infección. El avance y perfeccionamiento de los tratamientos han prolongado la vida de los pacientes y esto ha favorecido el mejor estudio y compresión de los diferentes eventos adversos, relacionados con la administración de quimioterapia.
Cancer is a global health problem. Multiple factors related to the disease and treatments cause a special predisposition to infections in the cancer patient. Sepsis is an important cause of morbidity and mortality. A descriptive cross-sectional study was carried out, where all sepsis events confirmed by microbiology were included, in patients with solid tumors in chemotherapy, treated at the Medical Oncology service of the Hospital Clinico Quirúrgico Hermanos Ameijeiras, from January 2015 to January 2017, whose objective was to describe their behavior. The mean age was 53 years (32.3%) and male patients predominated (56.5%). Digestive tract tumors, lung carcinomas, and soft tissue sarcomas accounted for 32.3, 25, and 13.7%, respectively. Of the 124 sepsis events, 39.5% had febrile neutropenia, followed by urinary sepsis (34.7%). In the group of patients with other infections, inflammatory novel lung disease predominated, followed by grade IV mucositis. There was no significant statistical association between the chemotherapy schedule and the appearance of infection. The advancement and improvement of the treatments have prolonged the life of the patients and this has favored the better study and understanding of the different adverse events related to the administration of chemotherapy.
Cancer is a global health problem. Multiple factors related to the disease and treatments cause a special predisposition to infections in the cancer patient. Sepsis is an important cause of morbidity and mortality. A descriptive cross-sectional study was carried out, where all sepsis events confirmed by microbiology were included, in patients with solid tumors in chemotherapy, treated at the Medical Oncology service of the Hospital Clinico Quirúrgico Hermanos Ameijeiras, from January 2015 to January 2017, whose objective was to describe their behavior. The mean age was 53 years (32.3%) and male patients predominated (56.5%). Digestive tract tumors, lung carcinomas, and soft tissue sarcomas accounted for 32.3, 25, and 13.7%, respectively. Of the 124 sepsis events, 39.5% had febrile neutropenia, followed by urinary sepsis (34.7%). In the group of patients with other infections, inflammatory novel lung disease predominated, followed by grade IV mucositis. There was no significant statistical association between the chemotherapy schedule and the appearance of infection. The advancement and improvement of the treatments have prolonged the life of the patients and this has favored the better study and understanding of the different adverse events related to the administration of chemotherapy.
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info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/publishedVersion
Source
Science and Health; Vol. 4 No. 3 (2020): Science and Health, september-december; 53-61
Ciencia y Salud; Vol. 4 Núm. 3 (2020): Ciencia y Salud, septiempre-diciembre; 53-61
2613-8824
2613-8816
10.22206/cysa.2020.v4i3
Ciencia y Salud; Vol. 4 Núm. 3 (2020): Ciencia y Salud, septiempre-diciembre; 53-61
2613-8824
2613-8816
10.22206/cysa.2020.v4i3