Perfil clínico del hipotiroidismo congénito en pacientes menores de 13 años. Consulta de endocrinología pediátrica, Hospital Infantil Dr. Robert Reid Cabral. Julio-diciembre 2017
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Subject
congenital hypothyroidism
clinical profile
auditory deficit
evolutionary development
hipotiroidismo congénito
perfil clínico
déficit auditivo
desarrollo evolutivo
clinical profile
auditory deficit
evolutionary development
hipotiroidismo congénito
perfil clínico
déficit auditivo
desarrollo evolutivo
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Volume Title
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Intituto Tecnológico de Santo Domingo (INTEC)
El objetivo del estudio fue caracterizar el perfil clínico del hipotiroidismo congénito en pacientes menores de 13 años de la Consulta de Endocrinología Pediátrica del Hospital Infantil Doctor Robert Reid Cabral. Se realizó un estudio descriptivo, observacional, de corte transversal con colección prospectiva de datos, donde fueron evaluados 22 pacientes y se revisaron sus expedientes clínicos, durante el período julio-diciembre 2017. Al concluir la investigación se pudo determinar que el 50 % de los pacientes fue diagnosticado con hipotiroidismo congénito antes de los tres meses de edad y el 18 % por encima de los 30 meses. La macroglosia y la hernia umbilical fueron las principales manifestaciones clínicas al momento del diagnóstico (40.9 %). La medición de la TSH fue utilizada en el 100 % de los casos. La ultrasonografía fue el estudio de imágenes más utilizado. En el 68.1 % de los pacientes con HC aún no se ha determinado la causa del HC. Dentro de los factores de riesgo presentes en la población de estudio sobresalieron los antecedentes familiares de enfermedad tiroidea y el síndrome de Down. El 59 % de los pacientes ha tenido una evolución clínica permanente. Los pacientes evaluados no presentaron déficit auditivo. En la evaluación psicológica se utilizó la prueba de Perfil de Desarrollo (DP3), realizada por el Departamento de Salud Mental del Hospital Infantil Doctor Robert Reid Cabral con entrevista directa a los padres, y el 40.9 % de los pacientes obtuvo nivel medio en la escala motriz, adaptativa, socioemocional y comunicativa de su desarrollo. El nivel cognitivo fue la función ejecutiva más afectada, fue muy bajo en el 45.4 % de los pacientes. El índice general de desarrollo fue muy bajo en el 45.4 %. El 75 % de los pacientes diagnosticados después de los 30 meses tuvo un índice general de desarrollo muy bajo. El 72.7 % de los pacientes diagnosticados antes de los primeros tres meses de vida tuvo un índice de desarrollo medio.
The objective of the study was to characterize the clinical profile of congenital hypothyroidism in patients under 13 years of Pediatric Endocrinology Consultation of the Children’s Hospital Doctor Robert Reid Cabral. A descriptive, observational, cross-sectional study was performed with prospective collection of data, where 22 patients were evaluated and their clinical records were reviewed, during the period July-December 2017. At the conclusion of the investigation it was determined that 50 % of the Patients were diagnosed with congenital hypothyroidism before 3 months of age and 18 % above 30 months. Macroglossia and umbilical hernia were the main clinical manifestations at the time of diagnosis (40.9 %). The TSH measurement was used in 100 % of the cases. Ultrasonography was the most used image study. In 68.1 % of patients with HC, the cause of HC has not yet been determined. The family history of thyroid disease and Down syndrome stood out among the risk factors present in the study population. 59 % of patients have had a permanent clinical evolution. The patients evaluated did not have auditory deficit. In the psychological evaluation we used the Development Profile test (DP3), carried out by the Department of Mental Health of the Dr. Robert Reid Cabral Children’s Hospital with direct interview with the parents, and 40.9 % of the patients obtained average level in the motor, adaptive, social-emotional and communicative scale of its development. The cognitive level was the executive function most affected, it was very low in 45.4 % of the patients. The overall rate of development was very low at 45.4 %. 75 % of patients diagnosed after 30 months had a very low overall developmental rate. 72.7 % of the patients diagnosed before the first 3 months of life had an average development index.
The objective of the study was to characterize the clinical profile of congenital hypothyroidism in patients under 13 years of Pediatric Endocrinology Consultation of the Children’s Hospital Doctor Robert Reid Cabral. A descriptive, observational, cross-sectional study was performed with prospective collection of data, where 22 patients were evaluated and their clinical records were reviewed, during the period July-December 2017. At the conclusion of the investigation it was determined that 50 % of the Patients were diagnosed with congenital hypothyroidism before 3 months of age and 18 % above 30 months. Macroglossia and umbilical hernia were the main clinical manifestations at the time of diagnosis (40.9 %). The TSH measurement was used in 100 % of the cases. Ultrasonography was the most used image study. In 68.1 % of patients with HC, the cause of HC has not yet been determined. The family history of thyroid disease and Down syndrome stood out among the risk factors present in the study population. 59 % of patients have had a permanent clinical evolution. The patients evaluated did not have auditory deficit. In the psychological evaluation we used the Development Profile test (DP3), carried out by the Department of Mental Health of the Dr. Robert Reid Cabral Children’s Hospital with direct interview with the parents, and 40.9 % of the patients obtained average level in the motor, adaptive, social-emotional and communicative scale of its development. The cognitive level was the executive function most affected, it was very low in 45.4 % of the patients. The overall rate of development was very low at 45.4 %. 75 % of patients diagnosed after 30 months had a very low overall developmental rate. 72.7 % of the patients diagnosed before the first 3 months of life had an average development index.
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info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/publishedVersion
Source
Science and Health; Vol. 4 No. 3 (2020): Science and Health, september-december; 131-139
Ciencia y Salud; Vol. 4 Núm. 3 (2020): Ciencia y Salud, septiempre-diciembre; 131-139
2613-8824
2613-8816
10.22206/cysa.2020.v4i3
Ciencia y Salud; Vol. 4 Núm. 3 (2020): Ciencia y Salud, septiempre-diciembre; 131-139
2613-8824
2613-8816
10.22206/cysa.2020.v4i3