Experiencia en el tratamiento con hormona de crecimiento en las pacientes con Síndrome de Turner
Date
Authors
Subject
Turner syndrome
growth hormone
High Cost Program
comorbilities
Síndrome de Turner
hormona del crecimiento
Programa de Alto Costo
comorbilidades
República Dominicana
growth hormone
High Cost Program
comorbilities
Síndrome de Turner
hormona del crecimiento
Programa de Alto Costo
comorbilidades
República Dominicana
Language:
Journal Title
Journal ISSN
Volume Title
Publisher
Intituto Tecnológico de Santo Domingo (INTEC)
En este trabajo se presenta la evaluación de la experiencia de 38 pacientes con Síndrome de Turner que recibieron hormona del crecimiento en el Hospital Infantil Dr. Robert Reid Cabral, dentro del Programa de Alto Costo del Ministerio de Salud Pública, durante el período comprendido entre enero de 2015 y enero de 2017. El grupo etario más representativo fue el de 11-14 años, el cual presentó una velocidad de crecimiento igual o mayor a 6 cm/año. La mayoría de estos pacientes proviene de Santo Domingo. El cariotipo de mayor porcentaje fue el tipo mosaico, con 71.1%. El 100% de las pacientes asistió a su cita periódica y recibió la hormona de crecimiento de manera continua.Las comorbilidades más frecuentes fueron las osteopatías y las endocrinopatías, más asociadas a cariotipo mosaico. En 15 casos hubo interrupción del tratamiento debido a clinodactilia pronunciada más escoliosis, cefalea persistente, cuadro de mareos y debilidad más cianosis. En 8 de estos casos se completó la edad ósea tope (12 años). Dos casos no respondieron al tratamiento. Hubo un caso que inició residencia fuera del país y otro de traspaso a un plan de seguro de salud privado. Los 23 casos restantes siguen activos en el Programa de Alto Costo. Las niñas con Turner llegan muy tarde por lo que no pueden obtener un beneficio mayor en su talla final.
In this paper, we evaluate the experience of 38 patients with Turner Syndrome receiving growth hormone in the Children’s Hospital Dr. Robert Reid Cabral in the High Cost program of the Ministry of Public Health, during the period January 2015 to January 2017. The most representative age group was 11-14 years old, which had a growth rate equal to or greater than 6 cm / year. The majority came from Santo Domingo. The highest percentage karyotype was the mosaic type with 71.1%. 100% of patients attended their regular appointment and received growth hormone continuously.The most common comorbidities were osteopathies and endocrinopathies, more associated with mosaic karyotype. In 15 cases, there was interruption of treatment due to pronounced clinodactyly plus scoliosis, persistent headache, dizziness and weakness plus cyanosis. In 8 cases, the peak bone age (12 years) was completed, two cases did not respond to treatment. One case changed to live outside the country and another case was transferred to private health insurance plan. The remaining 23 cases remain active in the High Cost Program. Girls with Turner arrive too late to get better benefits from their final stature.
In this paper, we evaluate the experience of 38 patients with Turner Syndrome receiving growth hormone in the Children’s Hospital Dr. Robert Reid Cabral in the High Cost program of the Ministry of Public Health, during the period January 2015 to January 2017. The most representative age group was 11-14 years old, which had a growth rate equal to or greater than 6 cm / year. The majority came from Santo Domingo. The highest percentage karyotype was the mosaic type with 71.1%. 100% of patients attended their regular appointment and received growth hormone continuously.The most common comorbidities were osteopathies and endocrinopathies, more associated with mosaic karyotype. In 15 cases, there was interruption of treatment due to pronounced clinodactyly plus scoliosis, persistent headache, dizziness and weakness plus cyanosis. In 8 cases, the peak bone age (12 years) was completed, two cases did not respond to treatment. One case changed to live outside the country and another case was transferred to private health insurance plan. The remaining 23 cases remain active in the High Cost Program. Girls with Turner arrive too late to get better benefits from their final stature.
Description
Type
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/publishedVersion
Source
Science and Health; Vol 2 No 1 (2018): Science and Health, january-april; 33-40
Ciencia y Salud; Vol. 2 Núm. 1 (2018): Ciencia y Salud, enero-abril; 33-40
2613-8824
2613-8816
10.22206/cysa.2018.v2i1
Ciencia y Salud; Vol. 2 Núm. 1 (2018): Ciencia y Salud, enero-abril; 33-40
2613-8824
2613-8816
10.22206/cysa.2018.v2i1