El origen de la variación de la energía libre asociada a la hidrólisis del ATP y la Enseñanza de la Bioquímica
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ATP
phosphoanhydride bonds
rich energy bonds
ATP
enlaces fosfoanhidros
enlaces ricoenergéticos
phosphoanhydride bonds
rich energy bonds
ATP
enlaces fosfoanhidros
enlaces ricoenergéticos
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Volume Title
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Instituto Tecnológico de Santo Domingo (INTEC)
Numerosos libros de texto utilizados en educacion secundaria y en el ambito de la ensenanza universitaria, mantienen que el trifosfato de adenosina ATP, es la “moneda energetica” de la celula, atribuyendole un caracter singular a los enlaces fosfoanhidros caracteristicos de esta biomolecula. Incluso se suele emplear la conocida como notacion de Lipmann, para simbolizar el supuesto caracter excepcional de estos “enlaces ricoenergeticos”. No obstante, la elevada energia libre estandar de la hidrolisis del ATP (ΔG°´= -30.5kJ/mol) no se debe a ningun enlace especial sino a varios factores electronicos y estericos, que incrementan la inestabilidad de la molecula y a la capacidad que tienen las celulas para alejar la relacion [ADP]/[ATP] diez ordenes de magnitud de la posicion de equilibrio.
Many Secondary and higher Education text books explain ATP is the “energy currency” of the cell, entrusting a special character to the characteristic phosphoanhydride bonds of this biomolecule. Even the so-called Lipmann notation is often used to symbolize the supposedly exceptional character of these “rich energy bonds”. However, the high standard free energy of ATP hydrolysis (ΔG°’= -30.5kJ / mol) is not due to any special bond but to several electronic and steric factors, which increase the instability of the molecule and the capacity of cells to keep relationship [ADP] / [ATP] ten orders of magnitude away from equilibrium position.
Many Secondary and higher Education text books explain ATP is the “energy currency” of the cell, entrusting a special character to the characteristic phosphoanhydride bonds of this biomolecule. Even the so-called Lipmann notation is often used to symbolize the supposedly exceptional character of these “rich energy bonds”. However, the high standard free energy of ATP hydrolysis (ΔG°’= -30.5kJ / mol) is not due to any special bond but to several electronic and steric factors, which increase the instability of the molecule and the capacity of cells to keep relationship [ADP] / [ATP] ten orders of magnitude away from equilibrium position.
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info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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info:eu-repo/semantics/publishedVersion
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Science, Environment and Climate; Vol. 1 No. 1 (2018): Science, Environment and Climate; 39-44
Ciencia, Ambiente y Clima; Vol. 1 Núm. 1 (2018): Ciencia, Ambiente y Clima; 39-44
2636-2333
2636-2317
10.22206/cac.2018.v1i1
Ciencia, Ambiente y Clima; Vol. 1 Núm. 1 (2018): Ciencia, Ambiente y Clima; 39-44
2636-2333
2636-2317
10.22206/cac.2018.v1i1