Factores sociodemográficos y clínicos asociados a mortalidad de pacientes con COVID-19 en República Dominicana
Date
Subject
Enfermedad por coronavirus 2019
República Dominicana
epidemiología
mortalidad
comorbilidad
Coronavirus disease 2019
Dominican Republic
epidemiology
mortality
comorbidity
República Dominicana
epidemiología
mortalidad
comorbilidad
Coronavirus disease 2019
Dominican Republic
epidemiology
mortality
comorbidity
Language:
Journal Title
Journal ISSN
Volume Title
Publisher
Intituto Tecnológico de Santo Domingo (INTEC)
Introducción:
La mortalidad por Covid-19 no ha sido descrita a nivel poblacional en República Dominicana.
Métodos:
Estudio de base poblacional, observacional, descriptivo y transversal, realizado durante el período 1ro de marzo 2020 - 31 de diciembre 2021. Se calcularon las medidas de tendencia central, odds ratio e intervalos de confianza al 95% (IC95%). Se realizó, además, un modelo de regresión logística. El error alfa se estimó en 0.05.
Resultados:
486,710 casos positivos a SARS-CoV-2 fueron reportados durante el período estudiado, siendo 264,744 (54.39%) femeninos. El grupo etario con mayor número de casos fue el de 30 a 39 años (n=118,499; 24.35%). Del total de casos, 8,484 (1.74%) tuvieron comorbilidades, siendo las más frecuentes la hipertensión (n=4,199; 49.49%) y diabetes mellitus (n=2,304; 27.15%). Los pacientes masculinos fueron 1.98 (IC95%: 1.86-2.1) veces más propensos a fallecer que los femeninos y el riesgo de morir incrementó de manera significativa a mayor edad del paciente, siendo la persona mayor de 79 años 166.5 (IC95%: 106.84-259.36) veces más proclive a fallecer. El paciente con COVID-19 y diabetes presentó un riesgo de morir de 56 (IC95%: 51-62) veces más, mientras que con hipertensión el riesgo fue 52 (IC95%:48-56) veces mayor. Al realizar el modelo de regresión logística, la hipertensión, asma, VIH, y diabetes mellitus tipo 2, se mantuvieron siendo factores de riesgo para fallecer por COVID-19.
Conclusiones:
En República Dominicana, los pacientes positivos al SARS-CoV2 de sexo masculino, por encima de los 79 años y con co-morbilidades (hipertensión, diabetes, asma y VIH) tuvieron una mayor probabilidad de fallecer por COVID-19. Estudios prospectivos se hacen necesarios para dilucidar la veracidad de la información presentada en este informe.
Introduction: COVID-19 associated mortality has not been described yet, at population-based level, in the Dominican Republic. Methods: Observational, descriptive, and cross-sectional, population-based study, implemented during the period of March 1st, 2020 – December 31st, 2021. Central trend measurements, odds ratios and 95% confidence intervals (CI 95%) were calculated. A logistic regression analysis was also performed. Alpha error was set at 0.05. Results: 486,710 SARS-CoV-2 positive cases were reported during the study period, with 264,744 (54.39%) being female. The age group with the highest number of reported cases was 30 to 39 years of age (n=118,499; 24.35%). Of the total number of cases, 8,484 (1.74%) had comorbidities, the most frequent being hypertension (n=4,199; 49.49%) and type 2 diabetes mellitus (n=2,304; 27.15%). Male patients were 1.98 (95% CI: 1.86-2.1) times more likely to die than female, and the risk of dying was 166.5 (CI95%: 106.84-259.36) times higher in patients older than 79 years of age. Patients with diabetes had 56-fold risk (IC95%: 51-62) of dying, while patients with hypertension were 52-fold (IC95%: 48-56). When the logistic regression model was performed, hypertension (OR=29.4), asthma (OR=5.6), HIV (OR=5.6) and type 2 diabetes mellitus (OR=4.5) remained as risk factors. Conclusions: In the Dominican Republic, male patients, older than 79 years of age and with co-morbidities (hypertension, asthma, HIV and diabetes), have a greater probability of dying of COVID-19. Prospective studies are necessary to elucidate the veracity of the information presented in this report.
Introduction: COVID-19 associated mortality has not been described yet, at population-based level, in the Dominican Republic. Methods: Observational, descriptive, and cross-sectional, population-based study, implemented during the period of March 1st, 2020 – December 31st, 2021. Central trend measurements, odds ratios and 95% confidence intervals (CI 95%) were calculated. A logistic regression analysis was also performed. Alpha error was set at 0.05. Results: 486,710 SARS-CoV-2 positive cases were reported during the study period, with 264,744 (54.39%) being female. The age group with the highest number of reported cases was 30 to 39 years of age (n=118,499; 24.35%). Of the total number of cases, 8,484 (1.74%) had comorbidities, the most frequent being hypertension (n=4,199; 49.49%) and type 2 diabetes mellitus (n=2,304; 27.15%). Male patients were 1.98 (95% CI: 1.86-2.1) times more likely to die than female, and the risk of dying was 166.5 (CI95%: 106.84-259.36) times higher in patients older than 79 years of age. Patients with diabetes had 56-fold risk (IC95%: 51-62) of dying, while patients with hypertension were 52-fold (IC95%: 48-56). When the logistic regression model was performed, hypertension (OR=29.4), asthma (OR=5.6), HIV (OR=5.6) and type 2 diabetes mellitus (OR=4.5) remained as risk factors. Conclusions: In the Dominican Republic, male patients, older than 79 years of age and with co-morbidities (hypertension, asthma, HIV and diabetes), have a greater probability of dying of COVID-19. Prospective studies are necessary to elucidate the veracity of the information presented in this report.
Description
Type
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/publishedVersion
Source
Science and Health; Vol. 9 No. 1 (2025): Science and Health, january-march; 7-17
Ciencia y Salud; Vol. 9 Núm. 1 (2025): Ciencia y Salud, enero-marzo; 7-17
2613-8824
2613-8816
10.22206/cisa.2025.v9i1
Ciencia y Salud; Vol. 9 Núm. 1 (2025): Ciencia y Salud, enero-marzo; 7-17
2613-8824
2613-8816
10.22206/cisa.2025.v9i1