Diabetes mellitus y su manejo en escenarios difíciles
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diabetes mellitus
quality of life
renal disease
liver failure
diabetes mellitus
calidad de vida
enfermedad renal
fallo hepático
quality of life
renal disease
liver failure
diabetes mellitus
calidad de vida
enfermedad renal
fallo hepático
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Journal Title
Journal ISSN
Volume Title
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Intituto Tecnológico de Santo Domingo (INTEC)
Introducción: la diabetes mellitus se produce por la alteración en el metabolismo de los carbohidratos, su prevalencia viene en aumento debido al incremento en la tasa de obesidad y los cambios en los hábitos nutricionales. En Colombia, alrededor de 8,36 % de la población padece diabetes tipo 2 y menos del 1 % diabetes tipo 1.
Metodología: se seleccionaron 51 artículos sobre diabetes y diferentes escenarios clínicos, publicados en su mayoría entre los años 2015-2021.
Resultados: en los pacientes con enfermedad hepática crónica, se aumenta la resistencia a la insulina e intolerancia a la glucosa; por esto, deben ser tratados en primera instancia con metformina o insulinas. En los diabéticos el riesgo cardiovascular se incrementa tanto para infarto como para accidente cerebrovascular. En estos, se puede realizar tratamiento con metformina, empagliflozina, entre otros. Los pacientes con falla renal tienen mayor riesgo de hipoglicemia por el metabolismo prolongado de la insulina como consecuencia de la filtración glomerular, en estos son útiles medicamentos como liraglutide y sus similares.
Conclusión: existen múltiples escenarios clínicos que se presentan en conjunto con la diabetes mellitus. Se deben tener en cuenta las múltiples comorbilidades de los pacientes al momento de instaurar un tratamiento y sus diferentes determinantes, para garantizar su efectividad.
Introduction: Diabetes mellitus is caused by alterations in carbohydrate metabolism and its prevalence is increasing due to the increase in the rate of obesity and changes in nutritional habits. In Colombia, about 8.36% of the population suffers from type 2 diabetes and less than 1% from type 1 diabetes. Methods: Fifty-one articles were selected, on diabetes and different clinical scenarios, mostly published between 2015-2021. Results: In patients with chronic liver disease, insulin resistance and glucose intolerance are increased; therefore, they should be treated in the first instance with Metformin or Insulin. In diabetics, cardiovascular risk is increased for both infarction and stroke. In these patients, treatment can be performed with Metformin, Empagliflozin, among others. Patients with renal failure have a higher risk of hypoglycemia due to prolonged insulin metabolism as a consequence of glomerular filtration; medications such as Liraglutide and similar drugs are useful in these patients. Conclusion: There are multiple clinical scenarios that occur in conjunction with diabetes mellitus. The multiple comorbidities of patients should be taken into account when instituting treatment and its different determinants to ensure the effectiveness of the treatment to be appropriate for the patients.
Introduction: Diabetes mellitus is caused by alterations in carbohydrate metabolism and its prevalence is increasing due to the increase in the rate of obesity and changes in nutritional habits. In Colombia, about 8.36% of the population suffers from type 2 diabetes and less than 1% from type 1 diabetes. Methods: Fifty-one articles were selected, on diabetes and different clinical scenarios, mostly published between 2015-2021. Results: In patients with chronic liver disease, insulin resistance and glucose intolerance are increased; therefore, they should be treated in the first instance with Metformin or Insulin. In diabetics, cardiovascular risk is increased for both infarction and stroke. In these patients, treatment can be performed with Metformin, Empagliflozin, among others. Patients with renal failure have a higher risk of hypoglycemia due to prolonged insulin metabolism as a consequence of glomerular filtration; medications such as Liraglutide and similar drugs are useful in these patients. Conclusion: There are multiple clinical scenarios that occur in conjunction with diabetes mellitus. The multiple comorbidities of patients should be taken into account when instituting treatment and its different determinants to ensure the effectiveness of the treatment to be appropriate for the patients.
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info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/publishedVersion
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Science and Health; Vol. 7 No. 2 (2023): Science and Health, April-June; 31-40
Ciencia y Salud; Vol. 7 Núm. 2 (2023): Ciencia y Salud, abril-junio; 31-40
2613-8824
2613-8816
10.22206/cysa.2023.v7i2
Ciencia y Salud; Vol. 7 Núm. 2 (2023): Ciencia y Salud, abril-junio; 31-40
2613-8824
2613-8816
10.22206/cysa.2023.v7i2