Intento suicida y psicosis debida a déficit de vitamina B12, a propósito de un caso
Date
Subject
Suicidal attempt
psychosis
paresthesias
B12 deficit
Intento suicida
psicosis
parestesias
déficit de B12
psychosis
paresthesias
B12 deficit
Intento suicida
psicosis
parestesias
déficit de B12
Language:
Journal Title
Journal ISSN
Volume Title
Publisher
Intituto Tecnológico de Santo Domingo (INTEC)
Introducción: El folato y la vitamina B12 juegan un papel importante en el correcto desarrollo, diferenciación y funcionamiento del Sistema Nervioso Central. Intervienen en la producción de mielina y son indispensables para numerosas reacciones que implican la metilación y biosíntesis de ácidos nucleicos, además de intervenir en la síntesis de proteínas, neurotransmisores, ácidos grasos y fosfolípidos. Su deficiencia se asocia a alteraciones cognitivas, irritabilidad, depresión, psicosis, demencia, entre otras.
Material y Métodos: En este trabajo se presenta el caso de una joven de 17 años, sin antecedentes mórbidos conocidos, que presentó cuadro de un mes de evolución, caracterizado por intento suicida, alucinaciones visuales y auditivas, idea delirante de daño tipo persecutoria, cefalea y parestesias en miembros inferiores. Ingresada en unidad de psiquiatría y consultada por departamento de neurología.
Se le realizaron analíticas y estudios especializados que incluían hemograma, glicemia, perfil renal, hepático, virales, electrolitos, perfil tiroideo, panel 6, tomografía de cráneo y EEG, sin evidencia patológica. Posteriormente con vitamina B12 y ácido fólico, evidenciando niveles de Vit B12 reducidos (110pg-ml), iniciamos la reposición de vitamina B12 intramuscular y añadimos Risperidona 3 mg cada 24 horas.
Conclusión: La paciente presentó remisión total de los síntomas, a partir del tratamiento de Vitamina B12 y los controles pertinentes del departamento de psiquiatría y hematología.
Introduction: Folate and vitamin B12 play an important role in the proper development, differentiation and functioning of the CNS. They intervene in the production of myelin, and are indispensable for numerous reactions involving the methylation and biosynthesis of nucleic acids. In addition to intervening in the synthesis of proteins, neurotransmitters, fatty acids and phospholipids. Its deficiency is associated with cognitive alterations, irritability, depression, psychosis, dementia,among others. Material and Methods: We present the case of a 17-year-old girl, with no known morbid history, who presented a month evolution, characterized by suicidal attempt, visual and auditory hallucinations, delusional idea of persecutory type damage, headache and paresthesias in lower limbs. Entered psychiatry unit and interconsultated with department of neurology. Analyzes and specialized studies were carried out that included hemogram, glycemia, renal, hepatic, viral, electrolyte, thyroid profile, panel 6, tomography of the skull and EEG, without pathological evidence. Subsequently, Vitamin B12 and folic acid were performed, evidencing reduced B12 Vit levels (110pg-ml), we started the replacement of intramuscular vitamin B12 and added Risperidone 3 mg every 24 hours. Conclusion: The patient presented total remission of symptoms. She is currently asymptomatic with Vitamin B12 maintenance treatment and controls by department of psychiatry and hematology.
Introduction: Folate and vitamin B12 play an important role in the proper development, differentiation and functioning of the CNS. They intervene in the production of myelin, and are indispensable for numerous reactions involving the methylation and biosynthesis of nucleic acids. In addition to intervening in the synthesis of proteins, neurotransmitters, fatty acids and phospholipids. Its deficiency is associated with cognitive alterations, irritability, depression, psychosis, dementia,among others. Material and Methods: We present the case of a 17-year-old girl, with no known morbid history, who presented a month evolution, characterized by suicidal attempt, visual and auditory hallucinations, delusional idea of persecutory type damage, headache and paresthesias in lower limbs. Entered psychiatry unit and interconsultated with department of neurology. Analyzes and specialized studies were carried out that included hemogram, glycemia, renal, hepatic, viral, electrolyte, thyroid profile, panel 6, tomography of the skull and EEG, without pathological evidence. Subsequently, Vitamin B12 and folic acid were performed, evidencing reduced B12 Vit levels (110pg-ml), we started the replacement of intramuscular vitamin B12 and added Risperidone 3 mg every 24 hours. Conclusion: The patient presented total remission of symptoms. She is currently asymptomatic with Vitamin B12 maintenance treatment and controls by department of psychiatry and hematology.
Description
Type
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/publishedVersion
Source
Science and Health; Vol 2 No 3 (2018): Science and Health, september-december; 55-61
Ciencia y Salud; Vol. 2 Núm. 3 (2018): Ciencia y Salud, septiembre-diciembre; 55-61
2613-8824
2613-8816
10.22206/cysa.2018.v2i3
Ciencia y Salud; Vol. 2 Núm. 3 (2018): Ciencia y Salud, septiembre-diciembre; 55-61
2613-8824
2613-8816
10.22206/cysa.2018.v2i3